The best way to protect an analytical column from fouling is to install a guard column between the injection valve and the analytical column. The guard column traps particulates, solvent impurities, and retained sample components. The ideal guard column should have no effect on the separation. In order to achieve this, a guard column with matching bonded phase and optimal hardware configuration should be selected. The Opti-Guard 3mm maintains the tool-free connectivity of the 1mm Opti-Guard, but incorporates a cartridge based format to allow for a larger bed with more capacity. The two-part holder is designed for use with any analytical column to provide vital protection from dirty samples and strongly retained contaminants. An auto-adjusting stem conforms to any tube stop depth for a perfect zero-dead-volume connection every time.
