Hi, If I use this on the spots where she goes and she goes to a new place to retaliate, would you recommend this to treat the whole house?

When you say treat the whole house do you mean as a preventative? If so I don't know how that would work, but if you are asking about treating other areas in the house she may urinate on then yes I would say that would work just fine.

Can I use this in my Rug Doctor?

You could but it would be unessary and pretty expensive. I would spot with the Simple Solution and then use the rug dr.

are the continuous bottles refillable

This version of our Simple Solution Urine Destroyer is not refillable. We hope that you may find this information helpful. For more information visit us at www,HeroPetBrands.com or call us at 800-272-6336. We are here to help! Sincerely, Hero Pet Brands

Is this a concentrate to be mixed with water?

There are no directions on the container stating that this should be mixed with water so I use it full strength. One time, I was running out so I put about 1/8 cup of water (1:1 ratio for amount left) into the dispenser bottle. It still worked on the odors I used it on. I would not recommend doing that though unless it's your last resort until you can get more. The product description states it contains water as one of the main ingredients so it is already diluted. One can presume it is to the proper strength.

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🧼 Erase pet messes, not memories — clean smarter, live fresher!

PREVENTS RE MARKING - Neutralizes odors fast and helps stop pets from returning to the same spot, keeping your home fresh longer.
VERSATILE SURFACE SAFETY - Effective and gentle on carpets, upholstery, hard floors, cement, and more—perfect for every corner of your home.
DOUBLE THE CLEANING POWER - Harnesses 2X pro-bacteria enzymes to obliterate pet urine stains and odors at the source.
KID PET FRIENDLY FORMULA - Formulated to be safe around your loved ones when used as directed, so you can clean with confidence.
PERMANENT ODOR ELIMINATION - Breaks down urine proteins instead of masking smells—say goodbye to lingering pet odors forever.

Simple Solution Urine Destroyer is a powerful enzymatic cleaner with 2X pro-bacteria strength designed to permanently remove pet urine stains and odors from carpets, upholstery, and other water-safe surfaces. Safe for use around children and pets, it neutralizes tough odors quickly and prevents pets from re-marking, making it an essential tool for maintaining a fresh, welcoming home environment.

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Manufacturer	OUT! International
Part number	11362-12P
Item Weight	383 g
Product Dimensions	7.95 x 24.31 x 7.95 cm; 382.83 g
Item model number	11362-12P
Size	2X-Large
Item Package Quantity	1
Batteries included?	No
Batteries Required?	No

Simple SolutionUrine Destroyer Enzymatic Cleaner | Pet Stain and Odor Remover with 2X Pro-bacteria Cleaning Power | 32 Ounces

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