






💡 Unlock your brain’s potential with every drop!
BioMatrix Pregnenolone is a premium sublingual liquid supplement designed for superior absorption—3X more effective than capsules. It supports memory, mood, and brain health by crossing the blood-brain barrier, while naturally balancing hormones and alleviating HPA axis dysfunction. With a 30-60 day supply in a compact 30 ml bottle, it’s a convenient, trusted choice for adults seeking cognitive and hormonal wellness.














| ASIN | B00U36X98Q |
| Best Sellers Rank | #45,145 in Health & Household ( See Top 100 in Health & Household ) #1,791 in Blended Vitamin & Mineral Supplements |
| Customer Reviews | 4.2 4.2 out of 5 stars (1,028) |
| Date First Available | October 22, 2013 |
| Is Discontinued By Manufacturer | No |
| Manufacturer | BioMatrix |
| Product Dimensions | 1.97 x 1.97 x 4.92 inches; 2.88 ounces |
J**N
Great solution
I love that there's a sublingual formula available, 1 ingredient and a quality solution for the menopause struggles I've had getting HRT through conventional doctors. I personally enjoy the taste, it feels like it instantly absorbs and begins working. Just 2 drops makes this little bottle a great value and convenient to bring with me in my purse. Seems I am already sleeping better too.
M**T
Amazing.
I bought this to attempt to get off BHRT and it's working! I am truly amazed. I've only been taking for one week- worked up from one drop, to two and now three per day. Stopped taking the BHRT a couple days ago. I thought that I'd be on these three cream hormones indefinitely, which is not cheap, but it seems that this is doing as it is supposed to.. getting my body to make it's own hormones again. I'm really amazed. I don't feel any strongly noticeable effects on my memory... though at a party last night I did remember every single persons name without hesitation, so that may be an effect of it. I also feel more happy and motivated, but that might just be from the success of getting my body to work correctly again. The first clear sign that this was working was that hair was growing more normally again.. my eyebrows have filled back in, I need to shave my legs more often. (The upside of rock-bottom testosterone was body hair becoming quite sparce). I am 47 and have been on BHRT for 7 years, so this prodoct is pretty close to a miracle for me. So glad I read Suzanne Sommers book and stumbled on the section on Pregnenolone! (That book is surprisingly well written). The week before I read about preg, I tried DHEA.. and immediately broke out like a teenager! I do think that this may be giving me energy at night.. so I can't sleep.. so I may have to take once only just at breakfast. For now I'm gonna try taking at breakfast and lunch. I highly recommend this product and truly stand in amazement. Such a simple remedy! I hope other women wanting to get off HRT will try it. Good luck!
J**N
Amazing-This really works 🤩 Thank you Biomatrix. ♥️ its products.
Age 73 on HRT estradiol patch, would love to keep my bones healthy, but started holding water from patch & progesterone wasn’t helping. No I wasn’t eating excessive salt either. I eat healthy & low carb, exercise regularly w much walking w golf & gym. Reduced estradiol patch to 1/2 still no relief. Pulled off patch completely-still holding water. I noticed the Pregnenolone I had in refrig. Looked up info & started taking 3 drops 2x’s today. Water started pouring out of me regularly all day (WOW). I wasn’t consuming additional water excessively. The white patches that were on my thighs when I’d press my hand (and release) are not there now—that’s fast. I understand it’s like the mother of all hormones & helps to regulate them all. I’ll continue to take this but in a lesser amount after tomorrow. Amazed at the fast results. Love Biomatrix products. Feel so relaxed & even fell asleep during a meditation this afternoon. Excited to see how my sleep is tonight. So very grateful.
S**Y
Helps calm me before bed
I am all over the place with this stuff after using it consistently for a month. I've had various hormone and egg reserve tests, etc., run over the years because my symptoms since my 20's have felt hormone related. All seem to test pretty normal, except I tend to have slightly low progesterone. Ok, fine, but as of late, I've been having a lot of issues sleeping even after working on my cortisol levels with an ND. I've tried supplementing with progesterone and it sort of helps, but sort of doesn't and can also make me feel wired. I've tried prescription pills, creams, and sublingual. I continue to have my hormone levels checked about ever 2 years and am also surprised the tests aren't really showing anything. Then I came across an article on pregnenolone being a precursor/ master hormone and figured I'd give it a try. I have noticed positive effects with sleeping a bit better at night, but it's a very fine balance. I do best on 2 - 3 drops. More helps me fall asleep easier, but then I wake up around 3 or 4am feeling wired. It might be one of those things where you need to gradually step up, but I have a feeling with how sensitive to hormones I am, I will probably just always remain at a lower dose, and that's ok because the positive effects even at a low dose are totally worth it. As far the nitty gritty, the dropper is pretty easy. Make sure you shake up really well and drop right away because it begins separating almost immediately. The taste is like rubbing alcohol, so not my favorite. It burns so I find I need to swirl it around my mouth quite a bit to cut it down, and then let is sit under my tongue for a couple of minutes. If I put it under there right away, it's way too strong and burns, but I've always had a more sensitive mouth and skin. I've mainly noticed improvement of sleep, but I do take 1 - 2 drops every morning and find it doesn't cause drowsiness, which is great. I'm not sure if it helps energy levels, but it certainly doesn't hurt them, for me at least.
V**A
Hope it is working to help with menopause anxiety and insomnia. I lick 2 drops off a saucer as recommended in another post - easiest way to ensure correct dose. Pleasant tasting.
S**H
Very effective
C**S
Do hormone/symptoms homework 1st before buying. Find the right dose for your condition. There are many conditions this treats not just hormonal. Read Dr John Lee and Ray Sahelian Books. Best advise is seek a good Doctor. This does work. Biomatrix company take a look. Age does matter. Suitable for middle to older men and women. Best second hand book for dosing is Pregnenolone nature's feel good hormone by Ray Sahelian M.D. **BUT REMEMBER we are all individuals !** Best taken in the morning, lick drops off a saucer then leave on tongue and lay down on bed for 10 mins so this gets into body systems. Can be used in combination of other Bioidentical hormones because as you get older your private parts loose their hormone making ability e.g so taking this if your periods have completely stopped, may be an unreliable source on its own. Depends on what you are using this for. It may be better on its own/ or combination of hormones. Been used for many conditions see Ray's book PMS, Prostrate cancer, Arthritis and Stress etc. Find a Doctor to test and dose for your condition. If you can.
K**K
The liquid is cloudy and requires shaking; it looks more like a suspension of powder than a solution. Pregnenolone is notoriously difficult to dissolve (the same brand DHEA drops are clear) so this is an indication it is what it claims to be. Should be fine (but expensive) for oral application in typical doses, but I have purchased it for lower dose topical use (to bypass the liver). I have therefore had to add my own penetration enhancers. So far it feels like it has the same effects as from other sources.
G**L
I ALWAYS check the expiry date! Technically still in date. Practically I've lost my money. There is NO way I could take more of the recommended dose of two small drops. This is a potent supplement and needs to be taken according the instructions. It expires in September 2022 therefore it has been a total loss of money. I can provide photo if necessary. Overall very disappointed.
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