

🔧 Lock it down like a pro — because your big jobs deserve red-hot reliability!
LOCTITE 37421 271 Red Heavy Duty Threadlocker is a professional-grade adhesive designed for securing large bolts and studs (1 inch/25 mm+) in automotive and industrial applications. It bonds quickly—setting in 10 minutes and fully curing in 24 hours—while resisting oil, chemicals, water, and temperatures up to 140°F. Trusted by OEMs and professionals alike, it delivers a durable, vibration-resistant hold that requires heat for disassembly, ensuring critical components stay locked until intentionally released.









| ASIN | B0028OJAIY |
| Best Sellers Rank | #9,104 in Automotive ( See Top 100 in Automotive ) #29 in Thread Lock Sealers |
| Brand | Loctite |
| Brand Name | Loctite |
| Color | Red |
| Compatible Material | Aluminum, Stainless Steel |
| Container Type | Tube |
| Customer Reviews | 4.8 out of 5 stars 1,046 Reviews |
| Full Cure Time | 24 Hours |
| Global Trade Identification Number | 00079340374218 |
| Included Components | (1) LOCTITE 271 Threadlocker for Automotive | Red, 6 ml Tube |
| Item Form | Tube |
| Item Package Quantity | 1 |
| Item Type Name | automotive-thread-lock-sealers |
| Item Weight | 0.01 Pounds |
| Manufacturer | Loctite |
| Material | Metal-based formulation |
| Material Type | Metal-based formulation |
| Model | 37421 |
| Other Special Features of the Product | Strong |
| Special Feature | Strong |
| Specific Uses For Product | Automotive, Industrial, DIY, Furniture, Heavy-Duty |
| UPC | 079340374218 |
| Viscosity | Low viscosity |
| Volume | 6 Milliliters |
| Water Resistance Level | Water Repellent |
A**M
Works
Love the lock and unlock tip and work good as well
M**E
Cannot beat for large hardware in critical application
Red Loctite is great for big, critical hardware applications. I usually default to blue Loctite for just about all the applications I find, but this time I was replacing wheel bearings and disc brake mounts on a 1 ton pickup, so that included both big hardware AND critical applications - really don't want those working loose over the next 50,000 miles!!! That would be a heck of a surprise. As usual, very easy to use in the tube - just apply a bit to the leading edge of the threads, run the bolt in, and torque it down. Of course, removing hardware with red Loctite is no joke but there's always heat if needed! That also means that the hold is fantastic and again, shouldn't work loose until it's intentionally persuaded with force and/or heat. So ease of removal is not easy at all - but that's the point! Applying out of the tube is very easy: just open the cap and cut off a tiny edge of the nozzle, then apply just a little bit (I've learned not to apply too much - it's just unneeded). Definitely not messy either, which is fantastic. When you apply it to threads, it really clings to the threads, allowing you time to get it in place and run down to torque. But it's also just runny enough to really work its way down into the threads. So overall, if you need to make sure a big piece of critical hardware doesn't move until you absolutely need it to, there's no better option that this red Loctite!
G**T
Screws won’t budge
Used this for a rifle stock that was held on by 2 screws that would always come loose when shooting. This stuff kept it locked down with no issues. Highly recommend
S**S
Awesome product.
This works again as advertised, i used it to install my V6 muzzle brake on my KSG and it worked great, that thing has not flinched a millimeter from when i first set it and it's been there for months and hundreds of rounds mostly slugs or 00 buck shot out of it, i think i've shot about 6 shells of birdshot in my life and not with this shotgun. It just works for weapons applications just make sure what you're using it for you're not intending to remove regularly cuz i would assume it would suck for you then, use the blue loctite instead which i have for regular bolts and such.
D**R
Great price
It's Loctite what can you say. It works how it should. Great price for the large bottle.
T**R
Loctite thread locker
Works great!
P**G
expensive for what you get
they sell it in milliliters to make it look like your getting a lot, but for the price your getting this tiny tube with just a bit inside. i haven't use it yet, because i don't need to lock things down just yet, i know the blue version tends to fail over time. but for the value, i might as well just epoxy things on in the future.
R**R
Keeps nuts from coming loose.
Nuts on bolts come loose, this stops that.